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Observe Carefully (3)pentobarbital will decrease the extent or impact of diazepam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Robust or moderate CYP3A4 inducers may maximize fee of diazepam elimination; hence, efficacy of diazepam can be reduced.Clients stabilized on corticosteroid therapy may po